Antimicrobial Array II - PT. RAFA

 

Antimicrobial Array II

 

Antimicrobial compounds have been used in food production to treat infections and to function as growth promoters. However, serious health concerns exist about the presence of antimicrobial compounds in food and the development of antibiotic resistant strains of micro-organisms due to inappropriate use in food producing animals. As a result of these concerns, many countries have banned or limited the use of antimicrobials in food producing animals and have set maximum residue limits (MRLs) for antimicrobial residues in food. It is evident that effective screening solutions for antimicrobials are essential.

  Low limits of detection   Generic detection of all major tetracycline metabolites and epimers   Applicable to multiple matrices  

Assay Limits of Detection

Assay Honey LOD (ppb) Milk LOD (ppb) Feed LOD (ppb) Prawn/Shrimp/Tissue LOD (ppb) Urine (ppb)
Quinolones (QNL) 3.44 1.0 20 5.0 4.5
Ceftiofur (CEFT) 2.31 1.5 15 4.6 3.3
Thiamphenicol (TAF) 0.66 0.5 15 1.3 0.7
Streptomycin (STR) 7.56 2.0 140 14.0 7.0
Tylosin (TYL) 1.01 2.5 10 0.9 0.5
Tetracycline (TCN) 8.65 1.0 35 4.8 1.3

Assay Specificity

Assay   % Cross Reactivity
Quinolones Norfloxacin 100
Ciprofloxacin 59
Danofloxacin 20
Difloxacin 8
Enoxacin 54
Enrofloxacin 76
Marbofloxacin 16
Ofloxacin 57
Orbifloxacin 23
Pipemidic acid 36
Sarafloxacin 6
Oxolinic Acid 12
Fleroxacin 32
Levofloxacin 32
Nadifloxacin 27
Pazufloxacin 7
Pefloxacin 84
Ceftiofur Ceftiofur 100
Desfuroylceftiofur 92
Thiamphenicol Florfenicol 100
Thiamphenicol 53
Streptomycin Streptomycin 100
Dihydrostreptomycin 182
Tylosin Tylosin 100
Tilmicosin 37
Tetracyclines Tetracycline 100
4-epitetracycline 87
Rolitetracycline 67
4-epioxytetracycline 52
Oxytetracycline 52
Chlortetracycline 51
Demeclocycline 41
Doxycycline 23
4-epichlortetracycline 20
Methacycline 11